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RoC puts PDRN in a drugstore retinol serum and says skin looks 7 years younger

RoC launched the serum in early November, pairing encapsulated retinol with PDRN made from ginseng callus cells instead of salmon DNA, at $28.49 for one ounce. Both headline numbers come from one 12-week study of 29 people that RoC reports on its product page. The 7-years-younger figure is based only on crow's feet and under-eye wrinkles at one month. The page doesn't say who ran or paid for the study, and we couldn't find it published anywhere.

What the products claim

RoC says its new Retinol Correxion Line Smoothing Triple Serum makes skin look 7 years younger in a month, and that 96% of users saw seven signs of aging reduced after one week.

The studies behind the claim

RoC's study

29People
What was tested
RoC Retinol Correxion Line Smoothing Triple Serum
Who ran it
Not named on the product page
Design
12-week study. The page doesn't say whether there was a comparison group.
How it was measured
Clinical grading within minutes and at one week, a corneometer for hydration at one week, and wrinkle measurements of crow's feet and under-eye lines at one month.
Who paid, and any ties
Not stated. RoC reports the results itself.
The paper
RoC product page footnotes

Why it matters

PDRN has moved from injections and salmon-sourced serums into the drugstore aisle. A years-younger number built from two wrinkle measures in a small, unpublished company study is worth reading for what it actually counted.

The story so far

  1. RoC announces the serum on National Retinol Day.

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